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2022 NFL Week 11 Predictions, Odds and Betting Previews

NFL Week 11
A general view of Lambeau Field during an NFL game between the Green Bay Packers and the New York Jets Sunday, Oct. 16, 2022, in Green Bay, Wis. (AP Photo/Jeffrey Phelps)

The tenth week of the current 2022 NFL season has gone by and now that Week 11 of the NFL has arrived, we are aware that the season is nearing its conclusion. As usual, JefeBet brings you the best NFL predictions for all games that will be played this week.

In total, there are 14 games scheduled to be played between November 17 and 21, taking into account that this week the Jacksonville Jaguars, Seattle Seahawks, Miami Dolphins and Tampa Bay Buccaneers are in their bye week. Without further ado, here are our predictions for the tenth week of the National Football League.

All odds shown are courtesy of BetMGM.

Predictions, Odds and Betting Preview for 2022 NFL Week 11 Games

Tennessee Titans (+130) vs Green Bay Packers (-155) / Thursday, November 17 / 8:15 PM E.T.

NFL Week 11 predictions betting odds
  • Titans Spread: +3.0.
  • Packers Spread: -3.0.
  • Over/Under: 42.

Week 11 of the NFL kicks off with a pretty interesting matchup when Titans and Packers meet on Thursday Night Football.

Tennessee got back to winning ways with a 10-17 victory over the Broncos and leads the AFC South with a 6-3 record by winning six of its last seven games. The Titans relied on Ryan Tannehill’s successful return after he threw two touchdown passes, while the defense allowed just 10 points for the third time in its last four games.

As for Green Bay, with a big 14-point fourth-period comeback against the Cowboys’ good defense, they ended a streak of five consecutive losses. Aaron Rodgers threw three touchdown passes for the first time this season and the Packers ended up winning 28-31 in overtime. Defensive problems continue to be the order of the day, as they conceded 27 points for the fourth time in the last six games, while the offense is slowly trying to wake up thanks to the ground game.

Prediction: Over.

[Titans vs Packers NFL Week 11 full betting preview here]

Chicago Bears (+135) vs Atlanta Falcons (-165) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Bears Spread: +3.0.
  • Falcons Spread: -3.0.
  • Over/Under: 50.

With the mission of returning to winning ways, the Bears and Falcons will face each other this coming Sunday in a new NFL game.

Chicago sits alone at the bottom of the NFC North after losing for the third consecutive time and falling to a 3-7 record. Another strong performance by QB Justin Fields, who rushed for more than 140 yards for the second consecutive game, did not prevent a 31-30 loss to the Lions. The defense again failed to get the job done by allowing more than 30 points for the third week in a row, despite the offense gaining more than 400 total yards for the first time this year and posting its fourth straight game with at least 29 touchdowns scored.

Meanwhile, the Falcons have lost ground in the NFC South, losing for the second consecutive time, this time 15-25 to the Panthers. Atlanta’s record has dropped to 4-6, and they gave the lead to the Buccaneers as a result of a terrible defensive effort in which they conceded 232 rushing yards to Carolina. On the offensive side, for the third time in the last four games they failed to score more than 17 points, losing each of those games.

Prediction: Bears to win.

[Bears vs Falcons NFL Week 11 full betting preview]

Carolina Panthers (+475) vs Baltimore Ravens (-650) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Panthers Spread: +12.0.
  • Ravens Spread: -12.0.
  • Over/Under: 43.5

With completely opposite realities in the current NFL season, next Sunday, Panthers and Ravens will collide on the gridiron.

Carolina now shares the bottom of the NFC South after posting a 15-25 win over the Falcons to move to a 3-7 mark. In one of the team’s few good offensive performances this year, the Panthers rushed for 232 yards against an Atlanta defense that was halted by this display. Defensively, things went very well once again, considering that two weeks ago (also against the Falcons) they allowed 34 points and 478 total yards.

For their part, the Ravens are coming off their bye week as leaders of the AFC North with a 6-3 record and a streak of three consecutive victories. In their last meeting, Baltimore defeated the Saints 27-13, allowing just 243 total yards and continuing their string of at least one fumble recovered in every game this season.

Prediction: Panthers Spread.

[Panthers vs Ravens NFL Week 11 full betting preview]

Cleveland Browns (+350) vs Buffalo Bills (-450) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Browns Spread: +9.5.
  • Bills Spread: -9.5.
  • Over/Under: 47.

After a weekend of losses, both the Browns and Bills will look to get back on the winning track when they meet in NFL Week 11.

Cleveland further complicated its postseason aspirations by losing 17-39 to the Dolphins, a direct rival. The Browns’ defense was vastly outplayed by Miami’s high-powered offense , giving up 491 total yards and the most points to an opponent this season. Thanks to this, Cleveland dropped to a 3-6 record with tough matchups looming against the Bills and Buccaneers.

As for Buffalo, one of the favorites to win the Super Bowl, they have it pretty tough after losing at home and in overtime, 33-30, to the Vikings. Not only did Minnesota record 481 total yards against one of the best defenses in the circuit, but the Bills also allowed 13 points in the final period to squander the lead. On offense, Josh Allen (who nearly missed the game due to elbow pain) threw two interceptions for the third game in a row. The offense also turned the ball over four times to Minnesota for losses.

Prediction: Over.

[Browns vs Bills NFL Week 11 full betting preview]

Washington Commanders (-135) vs Houston Texans (+115) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Commanders Spread: -2.5.
  • Texans Spread: +2.5.
  • Over/Under: 40.5

The Commanders will try to keep up their positive streak when they visit the Texans in another NFL Sunday game.

Washington is coming off a big upset last week when they beat the visiting Eagles, 32-21, to end Philadelphia’s undefeated streak. The Commanders played a perfect game against the best team of the season and evened their record to 5-5 in the hard-fought NFC East. Defensively, they forced four turnovers, one more than the Eagles had all season, while on offense they exploited their opponents’ shortcomings on the ground by recording 152 of their 330 total yards.

Meanwhile, Houston consolidated its position as the worst team of the current season by losing its fourth consecutive game and leaving a record of 1-7-1. The offense continues to be the main problem for the Texans, who have only surpassed 20 points once this season. On the defensive side, for the eighth time this year, they allowed more than 120 rushing yards in a 16-24 loss to the Giants.

Prediction: Commanders to win.

[Commanders vs Texans NFL Week 11 full betting preview]

Philadelphia Eagles (-400) vs Indianapolis Colts (+310) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Eagles Spread: -8.5.
  • Colts Spread: +8.5.
  • Over/Under: 44.5.

Another game that promises to be exciting is the match between the Eagles and Colts in NFL Week 11.

Philadelphia must quickly turn the page on its first loss of the season after losing its unbeaten home record to the Commanders, who defeated them 32-21. While the Eagles’ offense turned the ball over four times – only three for the entire season –Philadelphia’s defense once again struggled with their opponents’ ground attack and Washington managed to dominate the half 40:24 to 19:36.

For their part, the Colts reacted successfully to the change of head coach and led by Jeff Saturday returned to winning ways with a 25-20 victory over the Raiders. For just the second time this season, Indianapolis scored more than 20 points in a game thanks to Matt Ryan, who returned to the starting lineup in fine form after two missed games.

Prediction: Over.

[Eagles vs Colts NFL Week 11 full betting preview]

New York Jets (+145) vs New England Patriots (-175) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Jets Spread: +3.0.
  • Patriots Spread: -3.0.
  • Over/Under: 38.5.

Week 11 of the NFL will feature a very important matchup for the future of the AFC East when the Jets and Patriots meet in a divisional showdown.

The New York team is coming off a bye week after an impressive 17-20 win over the Bills. With a 6-3 record, the Jets are tied with Buffalo for second place in the division and must now face a New England team that already beat them 17-22 in Week 8. The key for the Jets is undoubtedly their defense, which ranks as one of the best in the circuit and has recovered at least one fumble in each of their games this year.

The Patriots also come into the game rested and eager to continue moving up in the division and in the American Conference itself. With a record of 5-4 and a streak of two straight victories, the New England team managed to qualify as one of the three wild cards despite not playing on Sunday. While the offense has been improving little by little, as is customary in Bill Belichick’s teams, the defense is one of the best in the league and is third in fumbles recovered with 17.

Prediction: Over.

[Jets vs Patriots NFL Week 11 full betting preview]

Los Angeles Rams (+145) vs New Orleans Saints (-175) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Rams Spread: +3.0.
  • Saints Spread: -3.0.
  • Over/Under: 39.

The Rams and Saints will face each other next Sunday in a duel between two teams that surprisingly occupy the last place in their respective divisions.

It seems like a matter of weeks before we officially see the reigning NFL champions eliminated after Los Angeles fell for the third consecutive week, this time to the Cardinals 27-17. The Rams offense is one of the worst in the league and all indications are that Cooper Kupp, their star receiver, will miss a few weeks due to injury. The defense continues to get the job done, but in the last six games, the Rams have scored more than 17 points only once.

As for the Saints, they dropped to the bottom of the NFC South after falling for the second straight week with a 10-20 loss to the Steelers. Injuries and inconsistency have been the main problems for a New Orleans team that has been unable to take advantage of being in the worst division in the entire NFL by failing to score more than 13 points in its last two games.

Prediction: Under.

[Rams vs Saints NFL Week 11 full betting preview]

Detroit Lions (+155) vs New York Giants (-190) / Sunday, November 20 / 1:00 PM E.T.

NFL Week 11 predictions betting odds
  • Lions Spread: +3.5.
  • Giants Spread: -3.5.
  • Over/Under: 46.5

Another interesting duel that NFL Week 11 will bring us is the confrontation of two teams that are coming from winning their respective games, the Lions and Giants.

Detroit earned its second consecutive win with a 31-30 victory over the Bears on the road. The Lions’ defense is still one of the worst in the league, if not the worst, but their offense, led by Jared Goff, shined once again after scoring more than 30 points for the fourth time this year. Let’s recall that Detroit also beat the Packers two weeks ago.

As for the Giants, they continue with their great season and after the bye week they had no problems to dispatch the Texans at home with a score of 24-16 and consolidate their position as one of the American Conference wild cards with a 7-2 record. Offensively, Daniel Jones and Saquon Barkley continue to cause damage, while the defense conceded 20 points or less for the sixth time this season.

Prediction: Over.

[Lions vs Giants NFL Week 11 full betting preview]

Las Vegas Raiders (+125) vs Denver Broncos (-150) / Sunday, November 20 / 4:05 PM E.T.

NFL Week 11 predictions betting odds
  • Raiders Spread: +2.5.
  • Broncos Spread: -2.5.
  • Over/Under: 41.5.

When the Raiders and Broncos clash at The High Mile this season, it will be the second meeting between two of the biggest letdowns of the 2022 NFL season.

The Raiders are in last place in the AFC West with a 25-20 loss to the Colts, their third loss in a row, leaving them with a 2-7 record. With several key injuries on offense, Las Vegas was held to 20 points for the third straight game, while the defense continues to be a disaster , allowing more than 400 total yards for the third time in the last four games , including 207 on the ground.

For their part, the Broncos will try to get back to winning ways at home and avenge a 23-32 loss in Las Vegas in week four. Denver’s offensive problems persisted against the Titans, one of the league’s top defenses, despite coming off a bye week. Although they have allowed their opponents more than 20 points only once, for the third time in the last five games they have failed to score more than 10 points.

Prediction: Broncos to win.

[Raiders vs Broncos NFL Week 11 full betting preview]

Dallas Cowboys (-120) vs Minnesota Vikings (+100) / Sunday, November 20 / 4:25 PM E.T.

NFL Week 11 predictions betting odds
  • Cowboys Spread: -1.0.
  • Vikings Spread: +1.0.
  • Over/Under: 47.5

The Cowboys and Vikings will meet over the weekend in one of the most important games of the day; a preview of what could be a postseason showdown in the NFC.

Dallas is coming off a 28-31 overtime loss to the Packers. The Cowboys’ great defense didn’t have a very good night at Lambeu Field, conceding three TDs to Aaron Rodgers and blowing a 14-point lead in the fourth quarter. This is the third time in the last four games that they have allowed more than 26 points, and for the first time they allowed more than 400 total yards. They now have a 6-3 record and own the second wild card in the conference.

As for the Vikings, they recently won their seventh straight game with a 33-30 overtime victory at Buffalo, demonstrating that they are built for great things this year. The Minnesota team rallied in the last quarter to take the win in one of the most spectacular games of the season and against one of the big favorites to win the title. While the offense racked up 481 total yards, the defense forced the Bills to lose four fumbles.

Prediction: Vikings to win.

[Cowboys vs Vikings NFL Week 11 full betting preview]

Cincinnati Bengals (-225) vs Pittsburgh Steelers (+180) / Sunday, November 20 / 4:25 PM E.T.

NFL Week 11 predictions betting odds
  • Bengals Spread: -4.5.
  • Steelers Spread: +4.5.
  • Over/Under: 41.5.

When the Bengals and Steelers meet for the second time this week following Pittsburgh’s victory in Week 1, one of the fiercest rivalries in football will have a new chapter.

Cincinnati is coming off its bye week and went into it with a convincing 42-21 win over the Panthers. The offense totaled 464 total yards, including 241 on the ground, thanks to Joe Mixon, who had four TDs on the ground and one passing. The defense also had a good day, forcing three turnovers, allowing less than 250 total yards for the second time in the last three games and putting the Bengals within one game of the Ravens at 5-4.

On the Pittsburgh side, they are coming off a 10-20 win over the Saints to drop their record to 3-6. While the Steelers have only scored more than 20 points once this season, against the Bengals, they held New Orleans to just 186 total yards while inflicting two turnovers to put on one of the best defensive displays of any team this season.

Prediction: Bengals Spread.

[Bengals vs Steelers NFL Week 11 full betting preview]

Kansas City Chiefs (-300) vs Los Angeles Chargers (+240) / Sunday, November 20 / 8:20 PM E.T.

NFL Week 11 predictions betting odds
  • Chiefs Spread: -7.0.
  • Chargers Spread: +7.0.
  • Over/Under: 49.5.

The top two teams in the AFC West will meet for the second time this season when the Chiefs and Chargers play on Sunday Night Football in NFL Week 11.

Kansas City picked up its third consecutive win last weekend by dispatching the Jaguars with a 17-27 score to consolidate its lead in the group with a 7-2 record. After racking up 480+ total yards for the third straight game and Patrick Mahomes receiving at least four touchdown passes for the third time, the offense’s three turnovers didn’t matter much. The defense also had a respectable night by not conceding more than 100 rushing yards for the first time in the last five games.

As for the Chargers, they lost ground in their quest to catch the Chiefs after falling 16-22 to the 49ers and dropping their record to 5-4. Los Angeles’ good offense didn’t have its best night against San Francisco’s excellent defense. Justin Herbert was pressured the entire game and with just 52 rushing yards, they finished the game with 238 total yards, the fewest of the season.

Prediction: Over.

[Chiefs vs Chargers NFL Week 11 full betting preview]

San Francisco 49ers (-350) vs Arizona Cardinals (+260) / Monday, November 21 / 8:15 PM E.T.

NFL Week 11 predictions betting odds
  • 49ers Spread: -7.5.
  • Cardinals Spread: +7.5.
  • Over/Under: 43.5

Next Monday, when the 49ers and Cardinals play each other in Mexico City, there will be a historic Monday Night Football game. This will be the fifth game to be played in Mexico overall and the first game there since 2019; it will be a rematch of the first NFL game played on Mexican soil on October 2, 2005.

With their second consecutive win, by beating the Chargers 16-22, the San Francisco team moved to 5-4, a half-game behind the Seahawks in the NFC West. For the third week in a row, the 49ers offense rushed for more than 100 yards, but their defense continues to be their most potent weapon by holding the Chargers to 238 total yards and not allowing 20 points or more for the seventh time.

As for the Cardinals, they snapped a two-game losing streak with a 27-17 win over the Rams to climb out of the bottom of the NFC West with a 4-6 record. Despite a strong offensive performance, Arizona may be without two key players: quarterback Kyler Murray, who has hamstring issues, and tight end Zach Ertz, who will likely miss the rest of the season.

Prediction: 49ers to win.

[49ers vs Cardinals NFL Week 11 full betting preview]

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