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NCAA College Football Week 12 Predictions, Odds and Betting Preview

UCLA football players greet fans as they leave the field after a 42-32 win over Utah in an NCAA college football game in Pasadena, Calif., Saturday, Oct. 8, 2022. (AP Photo/Ashley Landis)

We’re already in Week 12 of NCAA Football, which means that we are only three weeks away from the end of the regular season. Every game counts in this final stretch of the season, and several of the best teams in the country know this and will give their best to improve their ranking for the next round of the championship.

The action will begin on Tuesday, November 15, but most of the important matches will be played on Saturday, November 19. Today, at JefeBet we’ll go over the games involving teams from the Top 25 of the AP rankings, along with the available odds and predictions.

All odds shown below are courtesy of DraftKings.

Predictions and betting odds and for NCAA Football Week 12 Games

SMU Mustangs vs Tulane Green Wave / Thursday,November 17/ 8:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • SMU Moneyline: +135
  • Tulane Moneyline: -155
  • SMU Spread: +3
  • Tulane Spread: -3
  • Over/Under: 59

Prediction: Over

Navy Midshipmen vs UCF Knights / Saturday, November 19/ 12:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Navy Moneyline: +600
  • UCF Moneyline: -850
  • Navy Spread: +16 .5
  • UCF Spread: -16.5
  • Over/Under: 53

Prediction: UCF Spread

Austin Peay Governors vs Alabama Crimson Tide / Saturday, November 19/ 1:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Austin Peay Moneyline: N/A
  • Alabama Moneyline: N/A
  • Austin Peay Spread: N/A
  • Alabama Spread: N/A
  • Over/Under: N/A.

Prediction: N/A.

[Austin Peay vs Alabama full betting preview here]

Louisiana Ragin’ Cajouns vs Florida State Seminoles / Saturday, November 19/ 1:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Louisiana Moneyline: +1200
  • Florida State Moneyline: -2400
  • Louisiana Spread: +24
  • Florida State Spread: -24
  • Over/Under: 52

Prediction: Under

[Louisiana vs Florida State full betting preview here]

TCU Horned Frogs vs Baylor Bears / Saturday, November 19/ 1:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • TCU Moneyline: -140
  • Baylor Moneyline: +120.
  • TCU Spread: -2.5
  • Baylor Spread: +2.5.
  • Over/Under: 58

Prediction: Over

[TCU vs Baylor full betting preview here]

Illinois Fighting Illini vs Michigan Wolverines / Saturday, November 19/ 1:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Illinois Moneyline: +675
  • Michigan Moneyline: -975
  • Illinois Spread: +18
  • Michigan Spread: -18
  • Over/Under: 42

Prediction: Illinois Fighting Illini Spread

[Illinois vs Michigan full betting preview here]

Kansas State Wildcats vs West Virginia Mountaineers / Saturday, November 19/ 3:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Kansas State Moneyline: -285
  • West Virginia Moneyline: +240
  • Kansas State Spread: -7.5
  • West Virginia Spread: +7 .5
  • Over/Under: 54.5

Prediction: Under

Boston College Eagles vs Notre Dame Fighting Irish / Saturday, November 19/ 3:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Boston College Moneyline: +1100
  • Notre Dame Moneyline: -2100
  • Boston College Spread: +21
  • Notre Dame Spread: -21
  • Over/Under: 45

Prediction: Boston College Spread

Miami Hurricanes vs Clemson Tigers / Saturday, November 19/ 4:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Miami Moneyline: +750
  • Clemson Moneyline: -1150
  • Miami Spread: +19
  • Clemson Spread: -19
  • Over/Under: 48

Prediction: Clemson Tigers Spread

[Miami vs Clemson full betting preview]

Penn State Nittany Lions vs Rutgets Scarlet Knights / Saturday, November 19/ 4:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Penn State Moneyline: -1400
  • Rutgers Moneyline: +850
  • Penn State Spread: -19
  • Rutgers Spread: +19
  • Over/Under: 45

Prediction: Penn State Spread

Ohio State Buckeyes vs Maryland Terrapins / Saturday, November 19/ 4:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Ohio State Moneyline: -6000
  • Maryland Moneyline: +1800
  • Ohio State Spread: -27.5
  • Maryland Spread: +27.5
  • Over/Under: 65

Prediction: Over

[Ohio State vs Maryland full betting preview here]

Georgia Bulldogs vs Kentucky Wildcats / Saturday, November 19/ 4:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Georgia Moneyline: -2400
  • Kentucky Moneyline: +1200
  • Georgia Spread: -22 .5
  • Kentucky Spread: +22 .5
  • Over/Under: 49.5

Prediction: Kentucky Wildcats Spread

[Georgia vs Kentucky full betting preview here]

NC State Wolfpack vs Louisville Cardinals / Saturday, November 19/ 4:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • NC State Moneyline: +160
  • Louisville Moneyline: -190
  • NC State Spread: +4
  • Louisville Spread: -4
  • Over/Under: 45

Prediction: Louisville Moneyline

Texas Longhorns vs Kansas Jayhawks / Saturday, November 19/ 4:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Texas Moneyline: -325
  • Kansas Moneyline: +270
  • Texas Spread: -9
  • Kansas Spread: +9
  • Over/Under: 64

Prediction: Over

[Texas vs Kansas full betting preview]

Georgia Tech Yellow Jackets vs North Carolina Tar Heels / Saturday, November 19/ 6:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Georgia Tech Moneyline: +900
  • North Carolina Moneyline: -1500
  • Georgia Tech Spread: +21
  • North Carolina Spread: -21
  • Over/Under: 62.5

Prediction: North Carolina Spread

Tennessee Volunteers vs South Carolina Gamecocks / Saturday, November 19/ 8:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Tennessee Moneyline: -2100
  • South Carolina Moneyline: +1100
  • Tennessee Spread: -21.5
  • South Carolina Spread: +21.5
  • Over/Under: 66

Prediction: Under

[Tennesee vs South Carolina full betting preview here]

Ole Miss Rebels vs Arkansas Razorbacks / Saturday, November 19/ 8:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Ole Miss Moneyline: -130
  • Arkansas Moneyline: +110.
  • Ole Miss Spread: -2.5
  • Arkansas Spread: +2.5.
  • Over/Under: 60.5

Prediction: Over

USC Trojans vs UCLA Bruins / Saturday, November 19/ 9:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • USC Moneyline: -105
  • UCLA Moneyline: +105
  • USC Spread: -1.5
  • UCLA Spread: +1.5
  • Over/Under: 75.5

Prediction: Over

[USC vs UCLA full betting preview here]

UAB Blazers vs LSU Tigers / Saturday, November 19/ 10:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • UAB Moneyline: +480
  • LSU Moneyline: -645
  • UAB Spread: +14.5
  • LSU Spread: -14.5
  • Over/Under: 52.5.

Prediction: LSU Spread

[UAB vs LSU full betting preview here]

Colorado Buffaloes vs Washington Huskies / Saturday, November 19/ 10:00 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Colorado Moneyline: N/A
  • Washington Moneyline: N/A
  • Colorado Spread: +31.5
  • Washington Spread: -31 .5
  • Over/Under: 64

Prediction: Washington Spread

Utah Utes vs Oregon Ducks / Saturday, November 19/ 11:30 PM E.T.

College Football Predictions NCAA Football 2022 betting odds
  • Utah Moneyline: +140
  • Oregon Moneyline: -165
  • Utah Spread: +3
  • Oregon Spread: -3
  • Over/Under: 61.5.

Prediction: Over

[Utah vs Oregon full betting preview]


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