St. Louis Cardinals vs San Diego Padres Prediction, Pick, Odds, and Best Bets | Sep 21 2022

Cardinals vs Padres Best Bets and Betting Odds

On Wednesday, September 21, the St. Louis Cardinals (87-61) will pay a visit to the San Diego Padres (81-66) at PETCO Park in San Diego for a regular season matchup. As they work their way through the final third of the season, each of these teams will surely be looking for a win in this regular season game. Be sure to catch the action at 6:40 PM PT!

Let’s take a peek at how the Padres and Cardinals have performed against each other historically for context heading into Wednesday’s regular season contest.

This season, these ball clubs have played in four contests, and the Padres have claimed victory once against their opponents. In their last meeting on Tuesday, the San Diego Padres came out on top by a score of 5-0. The Padres had six runs and eight hits, while the Cardinals racked up 0 runs on two hits. We’ll see what plays out this time when these two teams go head to head at PETCO Park.

Betting Preview for the St. Louis Cardinals vs San Diego Padres MLB Game on September 21 2022

Where: PETCO Park in San Diego, CA

When: Wednesday, September 21, 2022 at 6:40 PM PT

Betting on the St. Louis Cardinals

Record: (87W-62L) | National League Central Standing: 1

The Cardinals outplayed the Cincinnati Reds 0-3 when they last played on Sunday, and we’ll be interested to see if this momentum continues. Overall this season, the Cardinals are currently batting .252 thanks in large part to their top hitter, Paul Goldschmidt, who is leading the squad with a batting average of .324. Defensively, they have an ERA of 3.79 and a .989 fielding percentage. Before you place your bet, don’t forget to review our evaluation of the odds below!

Absences and Injuries

It’s confirmed that the Cardinals are without Alexander Reyes (Shoulder), Tyler O’Neill (Hamstring), Jordan Hicks (Neck), and Drew VerHagen (Hip).

Betting on the San Diego Padres

Record: (82W-66L) | National League West Standing: 2

In their previous game on Sunday, the Padres were defeated by the Arizona Diamondbacks by a score of 1-6. Overall this season, the Padres are currently batting .240 due in large part to their hottest bat, Manuel Machado, who is riding high with a batting average of .300. In terms of defense, they carry an ERA of 3.87 and a .986 fielding percentage. Make sure you check out our odds analysis further down before selecting your picks!

Absences and Injuries

Per the list of injuries and inactive players the Padres will play without Thomas Pomeranz (Elbow) and Austin Adams (Forearm).

St. Louis Cardinals vs San Diego Padres | Moneyline, Over/Under and Point Spread Odds

Moneyline Pick: San Diego Padres (-124) at FanDuel

The Padres are considered the favorite in this regular season tiltball game. The club enters this game with a winning percentage of 53.33% for this month, accounting a total of eight wins. they’ve played. On the other side of things, the Cardinals’ winning percentage is larger at 61.11% for this month, a record of 11 victories in total.

Over/Under Pick: Under 7.5 Total Runs (-110) at FanDuel

In this matchup, we predict that the combined total number of runs scored for both teams will be under 7.5. Keep this in mind when you go to place your bet!

Runline Pick: San Diego Padres -1.5 Runs (+164) at FanDuel

The San Diego Padres will need to win by the amount of the spread or more in order to cover a runline of -1.5.

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