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Kansas City Chiefs vs San Francisco 49ers Best Bets and Betting Odds | October 23 2022

The San Francisco 49ers (3W-3L) will take on the Kansas City Chiefs (4W-2L) in Santa Clara on Sunday, October 23 at Levi’s Stadium. Both of these rivals will be pursuing a win, so remember to place your bets and then catch the excitement live at 1:25 PM PT!

For context related to this matchup, let’s see how the 49ers and the Chiefs have stacked up versus each other in the past. While these organizations have battled in four contests over the past few years, the home team, the 49ers, have claimed victory once against their opponents. In their latest meeting on August 14, 2021, the score was 16-19 in favor of the Kansas City Chiefs.

Betting Preview for the Kansas City Chiefs vs San Francisco 49ers NFL Week 7 Game on October 23 2022

Where: Levi’s Stadium in Santa Clara, California

When: Sunday, October 23, 2022 at 1:25 PM PT

Betting on the Kansas City Chiefs

Regular Season Record: (4W-2L) | American Football Conference Standing: 2

The Kansas City Chiefs have had fluctuating amounts of victories and losses lately and are 1st in the AFC West right now. In their most recent game on Sunday, October 16, the Chiefs were defeated by the Buffalo Bills 20-24. Does that bode well for them going into their game this week?

The Chiefs are averaging 289.33 passing yards and are also getting 4.3 yards per rush attempt. The team’s turnover margin is 1.0 and their average possession time this season is 30:58.

Absences and Injuries

As for inactive players, the Chiefs are without Blake Bell (Hip), Rashad Fenton (Hamstring), Derrick Gore (Thumb), Lucas Niang (Kneecap), Joe Thuney (Ankle), Tershawn Wharton (Knee – ACL), Trent McDuffie (Hamstring), Bryan Cook (Concussion), and Justyn Ross (Foot).

Betting on the San Francisco 49ers

Regular Season Record: (3W-3L) | National Football Conference Standing: 4

In their most recent game on Sunday, October 16, 2022, the 49ers were defeated by the Atlanta Falcons 28-14.

Absences and Injuries

At this time the 49ers will play without Charvarius Ward (Groin), Azeez Al-Shaair (Knee – MCL), Arik Armstead (Foot), Nick Bosa (Groin), Samson Ebukam (Achilles), Talanoa Hufanga (Concussion), Maurice Hurst Jr. (Biceps), Javon Kinlaw (Knee), Trey Lance (Ankle), Jordan Matthews (Knee – ACL), Mike McGlinchey (Calf), Colton McKivitz (Knee – MCL), Elijah Mitchell (Knee – MCL), Emmanuel Moseley (Knee – ACL), Jason Verrett (Knee – ACL), Jimmie Ward (Hand), Trent Williams (Ankle), Jordan Willis (Undisclosed), Kalia Davis (Undisclosed), and Drake Jackson (Knee).

Kansas City Chiefs vs San Francisco 49ers | Moneyline, Over/Under and Point Spread Odds

Moneyline Pick: Kansas City Chiefs (-136) at FanDuel

The Kansas City Chiefs are considered the favorite. The team enters the game with a winning percentage of 50%. Comparatively, the San Francisco 49ers’ winning percentage is 50%.

Over/Under Pick: Over 48.5 Points (-114) at FanDuel

During the regular season, the San Francisco 49ers have recorded an average of 20.33 points per game. The Kansas City Chiefs have logged 29.83 points.

Spread Pick: San Francisco 49ers 2.5 Points (-115) at FanDuel

The San Francisco 49ers will need to lose by less than the amount of the spread or win outright in order to cover.

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